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Allele : Tg(TcraBC10,TcrbBC10)3Chi transgene insertion 3, Francis Chisari

Primary Identifier  MGI:5648061 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(TcraBC10,TcrbBC10)3Chi
Strain of Origin  BALB/cByJ or C57BL/6J Is Recombinase  false
Is Wild Type  false
description  TCR expression cassettes into which the TCRalpha and TCRbeta cDNA sequences had been cloned were co-injected into (BALB/cByJ x C57BL/6J)F2 fertilized oocytes.
molecularNote  Rearranged Valpha13.1 JalphaNEW06 and Vbeta8.1 Jbeta1.2 were obtained from K-restricted CD8<+> cytotoxic T lymphocyte clone BC10 which recognizes an epitope located between residues 93-100 in the hepatitis B virus core/nucleocapsid (COR93). TCR sequences were cloned into TCR cassette expression vectors (pTalpha and pTbeta) and co-injected.
  • mutations:
  • Insertion
  • synonyms:
  • BC10.3 TCR transgenic,
  • BC10.3 TCR transgenic,
  • Cor93 TCR transgenic,
  • Cor93 TCR transgenic
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1 Feature

Trail: Allele

Genome

2 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

7 Publication categories

Trail: Allele