Primary Identifier | MGI:5648061 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(TcraBC10,TcrbBC10)3Chi |
Strain of Origin | BALB/cByJ or C57BL/6J | Is Recombinase | false |
Is Wild Type | false |
description | TCR expression cassettes into which the TCRalpha and TCRbeta cDNA sequences had been cloned were co-injected into (BALB/cByJ x C57BL/6J)F2 fertilized oocytes. |
molecularNote | Rearranged Valpha13.1 JalphaNEW06 and Vbeta8.1 Jbeta1.2 were obtained from K-restricted CD8<+> cytotoxic T lymphocyte clone BC10 which recognizes an epitope located between residues 93-100 in the hepatitis B virus core/nucleocapsid (COR93). TCR sequences were cloned into TCR cassette expression vectors (pTalpha and pTbeta) and co-injected. |