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Protein Coding Gene : Unc13c unc-13 homolog C

Primary Identifier  MGI:2149021 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  208898
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable calmodulin binding activity and syntaxin-1 binding activity. Involved in negative regulation of synaptic plasticity and synaptic vesicle exocytosis. Acts upstream of or within chemical synaptic transmission. Is active in calyx of Held and parallel fiber to Purkinje cell synapse. Is expressed in several structures, including brain; limb interdigital region; molar; olfactory epithelium; and spinal cord mantle layer. Orthologous to human UNC13C (unc-13 homolog C).
PHENOTYPE: Homozygous mutant mice demonstrate an impaired ability to learn complex motor tasks, putatively due to an observed increase in paired-pulse facilitation. [provided by MGI curators]
  • synonyms:
  • DNA segment, Chr 9, ERATO Doi 414, expressed,
  • 1500037O19Rik,
  • MGI:1196392,
  • RIKEN cDNA 1500037O19 gene,
  • unc-13 homolog C,
  • Unc13c,
  • Munc13-3,
  • MGI:2143201,
  • Unc13h3,
  • unc13 homolog (C. elegans) 3,
  • AU019458,
  • D9Ertd414e,
  • MGI:1917504,
  • MGC:40770,
  • expressed sequence AU019458

Features --> Cross References

Genome

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1 Involved In Mutations

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

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