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Protein Coding Gene : Klc1 kinesin light chain 1

Primary Identifier  MGI:107978 Organism  mouse, laboratory
Chromosome  12 NCBI Gene Number  16593
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0)

Predicted to enable kinesin binding activity and tubulin binding activity. Involved in stress granule disassembly. Acts upstream of or within axo-dendritic transport. Located in several cellular components, including axon; ciliary rootlet; and cytosol. Part of kinesin complex. Is expressed in gut; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in Alzheimer's disease and relapsing-remitting multiple sclerosis. Orthologous to human KLC1 (kinesin light chain 1).
PHENOTYPE: Mice homozygous for disruptions in this gene are significantly smaller than normal. [provided by MGI curators]
  • synonyms:
  • expressed sequence AI874768,
  • Kns2,
  • Klc1,
  • kinesin light chain 1,
  • MGD-MRK-36558,
  • AI874768,
  • kinesin 2,
  • MGI:2144913

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

2 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

16 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For