Primary Identifier | MGI:107978 | Organism | mouse, laboratory |
Chromosome | 12 | NCBI Gene Number | 16593 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0) Predicted to enable kinesin binding activity and tubulin binding activity. Involved in stress granule disassembly. Acts upstream of or within axo-dendritic transport. Located in several cellular components, including axon; ciliary rootlet; and cytosol. Part of kinesin complex. Is expressed in gut; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in Alzheimer's disease and relapsing-remitting multiple sclerosis. Orthologous to human KLC1 (kinesin light chain 1). PHENOTYPE: Mice homozygous for disruptions in this gene are significantly smaller than normal. [provided by MGI curators] |