Type | MGI:General | Description | pups nursing on dams administered doxycycline from P1 to P14 exhibit a 60% decrease of vWF+ intraacinous vessels in lungs at P14, indicating inhibition of pulmonary vascular development pups nursing on dams administered doxycycline from P1 to P14 exhibit a 70% increase in muscularization of pulmonary vessels, a 2-fold increase in medial wall thickness of vessels, and increased vessels with proliferating cells in the lungs, indicating pulmonary vascular remodeling |