| Primary Identifier | MGI:1353623 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 30945 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable ubiquitin conjugating enzyme binding activity and ubiquitin protein ligase activity. Involved in regulation of protein catabolic process at postsynapse, modulating synaptic transmission. Located in postsynapse. Is active in glutamatergic synapse and hippocampal mossy fiber to CA3 synapse. Is expressed in several structures, including central nervous system; dorsal root ganglion; genitourinary system; retina; and tooth. Orthologous to human RNF19A (ring finger protein 19A, RBR E3 ubiquitin protein ligase). PHENOTYPE: Mice homozygous for a gene-trapped allele exhibit decreased adult neurogenesis and enhanced long-term potentiation in the hippocampal dentate gyrus region, hyperactivity in a familiar environment, and a specific deficit in contextual fear conditioning, but not in other types of learning and memory. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
