| Primary Identifier | MGI:1196274 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 52276 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to be involved in mitotic metaphase chromosome alignment. Predicted to act upstream of or within cell division. Located in chromocenter. Is expressed in several structures, including central nervous system; early embryo; gonad; metanephros; and retina. Orthologous to human CDCA8 (cell division cycle associated 8). PHENOTYPE: Mice homozygous for a reporter allele exhibit early embryonic lethality due to mitotic defects associated with abnormal microtubule organization and mislocalization of the chromosomal passenger protein complex. Blastocysts fail to develop past E3.5 and undergo apoptosis by E5.5. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
