| Primary Identifier | MGI:1346526 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 16912 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable endopeptidase activity and proteasome binding activity. Acts upstream of or within antigen processing and presentation and response to bacterium. Part of proteasome core complex and spermatoproteasome complex. Is expressed in thymus primordium. Human ortholog(s) of this gene implicated in autoimmune disease (multiple); lymphoma; proteasome-associated autoinflammatory syndrome 3; and renal cell carcinoma. Orthologous to human PSMB9 (proteasome 20S subunit beta 9). PHENOTYPE: Mice homozygous for disruptions in this gene have a grossly normal phenotype but suffer from increased susceptibility to some viruses and have an increased risk of tumor development. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
