| Primary Identifier | MGI:2386266 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | C3 |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | 3.5 kb of the gene, a region including exon 24, was replaced with a neomycin resistance cassette via homologous recombination. Western blot analysis showed an absence of C3 beta-chain protein in the serum of homozygous mutant animals. Similarly, ELISA assay did not detect C3 protein in serum from homozygous animals. |
