Primary Identifier | MGI:4830540 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Speg |
Transmission | Germline | Strain of Origin | 129S2/SvPas |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exons 8 through 10 were replaced with a lacZ and neo cassette. The absence of protein expression of both alpha and beta isoforms was confirmed by western blot analysis on heart extracts. Beta-galactosidase staining confirmed expression of the reporter gene in the heart. |