| Primary Identifier | MGI:2143977 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 103537 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable NuA4 histone acetyltransferase complex binding activity; chromatin binding activity; and methylated histone binding activity. Acts upstream of or within embryonic skeletal system development. Predicted to be located in chromosome. Predicted to be part of NuA4 histone acetyltransferase complex and nucleosome. Predicted to be active in nucleus and site of double-strand break. Is expressed in several structures, including early conceptus; forelimb bud; gonad; neural retina; and skeletal muscle tissue. Orthologous to human MBTD1 (mbt domain containing 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit neonatal lethality and severe abnormalities in hematopoietic stem cell function and skeletal formation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
