| Primary Identifier | IPR037198 | Type | Homologous_superfamily |
| Short Name | MutL_C_sf |
| description | MutL and MutS are key components of the DNA repair machinery that corrects replication errors []. MutS recognises mispaired or unpaired bases in a DNA duplex and in the presence of ATP, recruits MutL to form a DNA signalling complex for repair. The N-terminal region of MutL contains the ATPase domain and the C-terminal is involved in dimerisation []. The structure of the C-terminal domain of MutL consists of two different alpha+beta (sub)domains, both composed of two layers (alpha/beta) with antiparallel sheet, where the second domain is inserted in the first one. |
