| Primary Identifier | MGI:2444084 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 244202 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable ATP hydrolysis activity and GTPase activity. Involved in defense response to fungus; positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; and positive regulation of inflammatory response. Predicted to be located in cytoplasmic side of plasma membrane; cytosol; and nucleus. Predicted to be active in cytoplasm. Is expressed in back skin. Orthologous to human NLRP10 (NLR family pyrin domain containing 10). PHENOTYPE: Mice homozygous for a knock-out allele display a global defect in adaptive immune responses with impaired dendritic cell migration to lymph nodes. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
