| Primary Identifier | MGI:2143854 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 103468 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0) Predicted to be a structural constituent of nuclear pore. Predicted to be involved in several processes, including nuclear pore complex assembly; nucleocytoplasmic transport; and post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery. Predicted to act upstream of or within mRNA transport and protein transport. Predicted to be located in nuclear membrane and nuclear periphery. Predicted to be part of nuclear pore outer ring. Predicted to colocalize with kinetochore. Is expressed in embryo and neural tube. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome; nephrotic syndrome type 11; and ovarian dysgenesis 6. Orthologous to human NUP107 (nucleoporin 107). PHENOTYPE: Mice homozygous for a CRISPR-generated allele exhibit reduced female fertility. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
