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Protein Coding Gene : Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide

Primary Identifier  MGI:109194 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  22629
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables actin binding activity; protein domain specific binding activity; and transmembrane transporter binding activity. Involved in presynaptic modulation of chemical synaptic transmission. Acts upstream of or within intracellular protein transport and negative regulation of dendrite morphogenesis. Located in cytoplasm. Is active in cerebellar granule cell to Purkinje cell synapse and presynapse. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human YWHAH (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta).
PHENOTYPE: Mice homozygous for a null allele exhibit normal oogenesis, in vitro oocyte maturation and in vivo breeding. [provided by MGI curators]
  • synonyms:
  • 14-3-3 eta,
  • tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide,
  • Ywhah,
  • MGD-MRK-38238

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

6 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

20 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For