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Allele : In(10)17Rk inversion, Chr 10, Roderick 17

Primary Identifier  MGI:3790439 Allele Type  Chemically induced (other)
Gene  In(10)17Rk Strain of Origin  DBA/2J
Is Recombinase  false Is Wild Type  false
molecularNote  This triethylene melamine-induced inversion of approximately 60 cM causes a homozygous pygmy phenotype, it is allelic by complementation test with Hmga2pg, the distal breakpoint is in intron 3 of Hmga2, and the proximal breakpoint is in intron 2 of Txlnb. A 3.7 kb fusion transcript of Hmga2 exons 4 and 5 and Txlnb exons 1 and 2 is produced. No other Txlnb transcript was found by northern blot of homozygous heart or femur.
  • mutations:
  • Inversion
  • synonyms:
  • pygmy Jackson,
  • Hmga2<pg-J>,
  • In17Rk,
  • pygmy Jackson,
  • In17Rk,
  • Hmga2<pg-J>
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1 Feature

Trail: Allele

Genome

0 Expresses

1780 Mutation Involves

Trail: Allele

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

6 Publication categories

Trail: Allele