Primary Identifier | MGI:3790439 | Allele Type | Chemically induced (other) |
Gene | In(10)17Rk | Strain of Origin | DBA/2J |
Is Recombinase | false | Is Wild Type | false |
molecularNote | This triethylene melamine-induced inversion of approximately 60 cM causes a homozygous pygmy phenotype, it is allelic by complementation test with Hmga2pg, the distal breakpoint is in intron 3 of Hmga2, and the proximal breakpoint is in intron 2 of Txlnb. A 3.7 kb fusion transcript of Hmga2 exons 4 and 5 and Txlnb exons 1 and 2 is produced. No other Txlnb transcript was found by northern blot of homozygous heart or femur. |