Primary Identifier | MGI:5524121 | Allele Type | Targeted |
Attribute String | Hypomorph | Gene | Fat1 |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A loxP site was inserted upstream of exon 24. An FRT- and loxP-flanked neomycin resistance cassette was inserted downstream of exon 25. Cre-mediated recombination removed the neomycin resistance cassette and exons 24 to 25, which encode the transmembrane domain. |