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Protein Coding Gene : Dtymk deoxythymidylate kinase
Primary Identifier  MGI:108396 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  21915
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables thymidylate kinase activity. Acts upstream of or within cellular response to growth factor stimulus; dTDP biosynthetic process; and nucleoside monophosphate phosphorylation. Predicted to be located in mitochondrial matrix. Predicted to be active in mitochondrion and nucleus. Is expressed in several structures, including alimentary system; forebrain; genitourinary system; midbrain; and respiratory system. Orthologous to human DTYMK (deoxythymidylate kinase).
PHENOTYPE: Homozygous mice for a null allele exhibit embryonic lethality before E12.5. [provided by MGI curators]
  • synonyms:
  • thymidylate kinase,
  • TYPK,
  • CDC8,
  • AU044245,
  • mtmk,
  • MGI:1261792,
  • expressed sequence AU044245,
  • D10Ertd203e,
  • DNA segment, Chr 10, ERATO Doi 203, expressed,
  • Dtymk,
  • MGD-MRK-37438,
  • Tmk,
  • deoxythymidylate kinase,
  • MGI:2138504
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Features --> Cross References

Genome

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2 Involved In Mutations

Trail: ProteinCodingGene

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

3 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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