| Primary Identifier | MGI:3830738 | Allele Type | Transgenic |
| Attribute String | Constitutively active, Inserted expressed sequence | Gene | Tg(Neurod2-Smo*A1)199Jols |
| Strain of Origin | C57BL/6 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The ND2:SmoA1 transgene contains the entire mouse smoothened homolog (Drosophila) Smo gene, with the constitutively active point mutation SmoA1 (W539L), driven by the 1kb mouse neurogenic differentiation 2 (Neurod2) promoter. Several lines were generated (lines 199, 193, 234, 255 and 201) with varying levels of expression (30-, 45-, 36-, 2- and 3-fold, respectively, relative to wild0type expression). |
