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Protein Coding Gene : Gng8 guanine nucleotide binding protein (G protein), gamma 8

Primary Identifier  MGI:109163 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  14709
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable G-protein beta-subunit binding activity. Acts upstream of or within cellular response to pheromone; nose development; and social behavior. Predicted to be located in plasma membrane. Predicted to be part of heterotrimeric G-protein complex. Is expressed in cochlear duct epithelium; retina; and spleen. Orthologous to human GNG8 (G protein subunit gamma 8).
PHENOTYPE: Homozygous inactivation of this gene results in a slow but progressive loss of vomeronasal neurons, impairment of specific vomeronasal-mediated behaviors such as maternal and intermale aggression, and reduced physiological responses to pheromonal stimulation. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-38207,
  • guanine nucleotide binding protein (G protein), gamma 8,
  • Gng8,
  • G(y)8

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

59 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

1 Driver For