Primary Identifier | MGI:1924427 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 109205 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables SUMO polymer binding activity. Involved in cochlea development. Acts upstream of or within inner ear morphogenesis; locomotory behavior; and sensory perception of sound. Located in nucleus. Is expressed in cerebellum Purkinje cell layer and forebrain. Orthologous to human SOBP (sine oculis binding protein homolog). PHENOTYPE: Homozygous mutant mice exhibit open-field hyperactivity and circling behavior from weaning. Their hearing thresholds are elevated at all frequencies; the hearing impairment does not progress over time. [provided by MGI curators] |