Primary Identifier | MGI:5496402 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Gt(ROSA)26Sor |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The targeting constructed inserted between exon 1 and 2 contained a floxed splice acceptor neomycin resistance cassette and translation initiation site with 2 polyadenylation sequences followed by a truncated Notch1 cDNA encoding the intracellular domain. Cre-mediated recombination is required to achieve expression of the Notch2 intracellular domain. |