| First Author | Hidai C | Year | 2005 |
| Journal | Anat Rec A Discov Mol Cell Evol Biol | Volume | 287 |
| Issue | 2 | Pages | 1165-75 |
| PubMed ID | 16302230 | Mgi Jnum | J:134127 |
| Mgi Id | MGI:3785034 | Doi | 10.1002/ar.a.20247 |
| Citation | Hidai C, et al. (2005) Overexpression of the Del1 gene causes dendritic branching in the mouse mesentery. Anat Rec A Discov Mol Cell Evol Biol 287(2):1165-75 |
| abstractText | In the present study, we established transgenic mice overexpressing Del1, a ligand of integrins, to examine the effect of overexpression of Del1 on vascular morphogenesis. In the wild-type mouse, mesenteric vessels are shaped like rakes consisting of a long stalk and short branches at the periphery. In contrast, those in transgenic mice showed typical dendritic architecture consisting of a few large primary branches with smaller spreading branches. The phenotype of mice overexpressing Del1 suggests the existence of a tissue-specific mechanism for branching morphogenesis in the mesentery. |
