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Allele : Jak1<em2Maak> Janus kinase 1; endonuclease-mediated mutation 2, Masashi Akiyama
Primary Identifier  MGI:6870532 Allele Type  Endonuclease-mediated
Attribute String  No functional change Gene  Jak1
Strain of Origin  C57BL/6JJcl Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR-targeting introduced two silent mutations (c.1788C to A (I596I) and c.1791T to C (Y597Y)) to avoid re-cleavage by Cas9.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Jak1<I596I/+;Y597Y/+>,
  • Jak1<I596I/+;Y597Y/+>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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0 Driven By

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Trail: Allele




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