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Allele : Sgca<tm2.1Kcam> sarcoglycan, alpha (dystrophin-associated glycoprotein); targeted mutation 2.1, Kevin P Campbell

Primary Identifier  MGI:3772335 Allele Type  Targeted
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Sgca
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  After germline-specific Cre-mediated excision of the floxed neomycin cassette achieved by crossing mice carrying the floxed allele with mice expressing either EIIa-cre or protamine 1-cre, the Sgca locus expresses a transcript bearing the H77C missense mutation. The mutant protein is expressed in the sarcolemma of striated muscles,
  • mutations:
  • Insertion
  • synonyms:
  • Sgca<H77C/H77C>,
  • H77C/H77C,
  • H77C/H77C,
  • Sgca<H77C/H77C>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele