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Protein Domain : Three prime repair exonuclease 2

Primary Identifier  IPR034926 Type  Family
Short Name  TREX2
description  TREX1 and TREX2 are DNAQ-like 3'-5' exonucleases that process the 3' termini during DNA replication, repair, and degradation [, ]. TREX1 is expressed in all cells, whereas TREX2 is expressed primarily in keratinocytes []. TREX2 plays an important function during DNA metabolism and cellular proliferation []. Its overexpression plays a role in developing the psoriasis phenotype [].

0 Child Features

1 Parent Features

2 Protein Domain Regions