| Primary Identifier | IPR005576 | Type | Domain |
| Short Name | Rpb7-like_N |
| description | Rpb7 is a subunit of eukaryotic RNA polymerase (RNAP) II that is homologous to Rpa43 of RNAP I, Rpc8/Rpc25 of RNP III, and RpoE of archaeal RNAP. Rpb7 binds to Rpb4 to form a heterodimer. This complex is thought to interact with the nascent RNA strand during RNA polymerase II elongation []and plays a part in transcription,mRNA transport and DNA repair []. In RNA polymerase I, Rpa43 is at least one of the subunits contacted by the transcription factor TIF-IA []. The N terminus of Rpb7 and homologues has a SHS2 domain that is involved in protein-protein interaction []. |
