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Allele : Msh6<tm1Rak> mutS homolog 6; targeted mutation 1, Raju Kucherlapati

Primary Identifier  MGI:1858014 Allele Type  Targeted
Attribute String  Null/knockout Gene  Msh6
Transmission  Germline Strain of Origin  STOCK 129/Sv and C57BL/6J and SJL
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance gene was inserted at codon 336 within exon 4 of the gene, resulting in a stop codon 21 nucleotides downstream. No transcript for the targeted gene was detected on Northern blots of RNA extracted from two double-targeted ES cell lines. No protein product for the targeted gene was detected on Western blots of protein extracted from two double-targeted ES cell lines.
  • mutations:
  • Insertion
  • synonyms:
  • Msh6-,
  • Msh6-
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

29 Publication categories

Trail: Allele