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Publication : Learning and anxiety in angiotensin-deficient mice.

First Author  Walther T Year  1999
Journal  Behav Brain Res Volume  100
Issue  1-2 Pages  1-4
PubMed ID  10212048 Mgi Jnum  J:54146
Mgi Id  MGI:1334144 Doi  10.1016/s0166-4328(98)00078-3
Citation  Walther T, et al. (1999) Learning and anxiety in angiotensin-deficient mice. Behav Brain Res 100(1-2):1-4
abstractText  Angiotensin II in the brain was shown to be involved in mechanisms influencing cardiovascular and electrolyte homeostasis, anxiety and learning. Here, we report behavioural studies in mice lacking angiotensinogen. We analysed learning and anxiety related behaviour using the Morris water maze task and the elevated plus maze task, respectively. In both tests no differences were found between control mice and angiotensin-deficient mice. This implicates that angiotensin does not influence learning and anxiety-related behaviour in mice under normal conditions.
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