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Protein Domain : Protein phosphatase 1 regulatory subunit 26

Primary Identifier  IPR026130 Type  Family
Short Name  PPP1R26
description  Protein phosphatase 1 regulatory subunit 26 (PPP1R26) interacts with and inhibits the phosphatase activity of protein phosphatase 1 (PP1) complexes []. The protein is widely expressed in multiple tissues in humans []. Although its exact biological function is not known, PPP1R26 may positively regulate cell proliferation, and has oncogenic characteristics - its expression in NIH3T3 fibroblasts has been shown to cause tumour development in nude mice [].

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1 Protein Domain Regions