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Protein Coding Gene : C1ql3 C1q-like 3

Primary Identifier  MGI:2387350 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  227580
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables identical protein binding activity. Involved in neurotransmitter receptor localization to postsynaptic specialization membrane and postsynaptic density assembly. Acts upstream of or within regulation of synapse organization. Located in extracellular region. Is active in glutamatergic synapse; hippocampal mossy fiber to CA3 synapse; and synaptic cleft. Is expressed in several structures, including adipose tissue; brain; cranial ganglion; genitourinary system; and hemolymphoid system. Orthologous to human C1QL3 (complement C1q like 3).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired coordination, hyperactivity, decreased anxiety-related response, impaired contextual conditioning behavior, impaired CPP, impaired conditioned taste aversion and reduced density of excitatory synapses. [provided by MGI curators]
  • synonyms:
  • MGI:2139035,
  • AI661623,
  • C1ql3,
  • K100,
  • RIKEN cDNA 1110065A22 gene,
  • MGI:1916171,
  • expressed sequence AI661623,
  • C1q-like 3,
  • 1110065A22Rik

Features --> Cross References

Genome

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

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Expression

Gene --> Expression annotations

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Disease

Mouse features --> Human diseases

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