Primary Identifier | MGI:891965 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 22365 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to be involved in intracellular protein transport and vesicle-mediated transport. Predicted to act upstream of or within protein transport. Located in Golgi membrane and endosome membrane. Human ortholog(s) of this gene implicated in severe congenital neutropenia 5. Orthologous to human VPS45 (vacuolar protein sorting 45 homolog). PHENOTYPE: A knock-out allele shows embryonic lethality around 7.5, with impaired germ layer formation. [provided by MGI curators] |