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Protein Coding Gene : Vps45 vacuolar protein sorting 45

Primary Identifier  MGI:891965 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  22365
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to be involved in intracellular protein transport and vesicle-mediated transport. Predicted to act upstream of or within protein transport. Located in Golgi membrane and endosome membrane. Human ortholog(s) of this gene implicated in severe congenital neutropenia 5. Orthologous to human VPS45 (vacuolar protein sorting 45 homolog).
PHENOTYPE: A knock-out allele shows embryonic lethality around 7.5, with impaired germ layer formation. [provided by MGI curators]
  • synonyms:
  • AI462172,
  • Vps45,
  • AW554165,
  • MGI:2139732,
  • vacuolar protein sorting 45,
  • mVps45,
  • expressed sequence AW554165,
  • MGI:2140005,
  • expressed sequence AI462172

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

6 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For