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Comment :

Type  MGI:General Description  apoptosis of lymphoid-primed multipotent progenitors (1.7-fold) and common lymphoid progenitors (2.5-fold) is increased compared to in control mice in competitive repopulation assays, mice exhibit reduced long term hematopoietic stem cells and impaired hematopoietic stem cell progenitor development compared with control mice after second transplant, bone marrow fails to rescue lethally irradiated recipients compared with wild-type bone marrow