Primary Identifier | MGI:3699248 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Trp53 |
Transmission | Germline | Strain of Origin | 129S4/SvJae-Tg(Prm-cre)70Og |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Threonine codons 76 (ACC) and 86 (ACT) were changed to alanine (GCC, GCT) (p.T76A, p.T86A). The loxP site flanked neomycin resistance gene cassette that was inserted into intron 6 was removed through subsequent Cre-mediated recombination. |