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Allele : Nucks1<tm1.2Vter> nuclear casein kinase and cyclin-dependent kinase substrate 1; targeted mutation 1.2, Vinay Tergaonkar
Primary Identifier  MGI:6294929 Allele Type  Targeted
Attribute String  Null/knockout Gene  Nucks1
Transmission  Germline Strain of Origin  (129S2/SvPas x C57BL/6NSlc)F1-Tg(CAG-EGFP,Acr-EGFP)2Osb
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted into intron 3 and an FRT site flanked neomycin resistance gene cassette and a second loxP site into intron 4. The neo cassette was removed through subsequent flp-mediated recombination. Exon 4 was deleted through subsequent cre-mediated recombination. Western blot analysis showed an absent of expression in mouse embryonic fibroblasts, liver, and epididymal adipose tissues.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Nucks1<->,
  • Nucks1<->
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1 Feature

Trail: Allele

Genome

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0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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