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Protein Coding Gene : Srsf10 serine and arginine-rich splicing factor 10
Primary Identifier  MGI:1333805 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  14105
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable RNA binding activity. Involved in RNA splicing, via transesterification reactions; cytosolic transport; and negative regulation of mRNA splicing, via spliceosome. Located in nucleoplasm. Is expressed in several structures, including branchial arch; central nervous system; foregut-midgut junction; musculature; and sensory organ. Orthologous to human SRSF10 (serine and arginine rich splicing factor 10).
PHENOTYPE: Mice homozygous for a null allele exhibit fetal and neonatal lethality associated with edema and cardiac defects. [provided by MGI curators]
  • synonyms:
  • Srsf10,
  • Nssr,
  • FUS interacting protein (serine-arginine rich) 1,
  • Sfrs13a,
  • TASR2,
  • NSSR2,
  • neural-salient serine/arginine-rich,
  • splicing factor, arginine/serine-rich 13A,
  • Fusip1,
  • Srsf13a,
  • SRrp40,
  • serine and arginine-rich splicing factor 10,
  • NSSR1,
  • FUSIP2,
  • serine/arginine-rich splicing factor 13A,
  • TASR1
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Features --> Cross References

Genome

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3 Involved In Mutations

Trail: ProteinCodingGene

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

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Function

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Interactions

4 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

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