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Protein Coding Gene : Anapc2 anaphase promoting complex subunit 2
Primary Identifier  MGI:2139135 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  99152
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable ubiquitin protein ligase binding activity. Involved in positive regulation of synapse maturation and positive regulation of synaptic plasticity. Predicted to be part of anaphase-promoting complex. Is expressed in central nervous system; limb; and neural retina. Orthologous to human ANAPC2 (anaphase promoting complex subunit 2).
PHENOTYPE: Homozygous mutation of this gene results in embryonic lethality before E6.5. Conditional ablation in the liver results in liver failure and premature death. [provided by MGI curators]
  • synonyms:
  • Emi4,
  • expressed sequence AL024279,
  • AL024279,
  • MGI:1927108,
  • APC2,
  • anaphase promoting complex subunit 2,
  • RIKEN cDNA 9230107K09 gene,
  • expressed during mesenchymal induction 4,
  • mKIAA1406,
  • Anapc2,
  • Imi4,
  • induced during mesenchymal induction 4,
  • 9230107K09Rik
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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Homology

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Interactions

39 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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