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Publication : Chromosomal localization of omega and trophoblast interferon genes in goat and sheep by fluorescent in situ hybridization.

First Author  Iannuzzi L Year  1993
Journal  J Hered Volume  84
Issue  4 Pages  301-4
PubMed ID  8340618 Mgi Jnum  J:14055
Mgi Id  MGI:62232 Doi  10.1093/oxfordjournals.jhered.a111343
Citation  Iannuzzi L, et al. (1993) Chromosomal localization of omega and trophoblast interferon genes in goat and sheep by fluorescent in situ hybridization. J Hered 84(4):301-4
abstractText  Fluorescent in situ hybridization (FISH) of the cattle cDNA probe bTP-509 to goat (Capra hircus L.) and sheep (Ovis aries L.) R-banded metaphase chromosomes localized the omega (IFNW) and trophoblast (IFNT) interferon genes to goat chromosome 8q15 and sheep chromosome 2p15. Caprine chromosome 8 and ovine chromosome 2p are equivalent in banding pattern to cattle chromosome 8. Since FISH has previously localized IFNW and IFNT genes to cattle chromosome 8q15 and river buffalo 3q15, the localization of IFNW and IFNT genes in goat and sheep provides evidence in support of the hypothesis that chromosome-banding homology among these four species is indicative of underlying genetic homology.
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