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Protein Domain : Nicking enzyme C-terminal middle helical domain

Primary Identifier  IPR040834 Type  Domain
Short Name  NES_C_h
description  This domain is found in nicking enzyme in S. aureus. NES initiates and terminates the transfer of plasmids that variously confer resistance to a range of drugs, including vancomycin and gentamicin. This domain is found in the C-terminal region of NES. The C-terminal region is required for conjugation and significantly impacts the catalytic activity of the N-terminal relaxase [].

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0 Protein Domain Regions