Primary Identifier | MGI:2183286 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Gstz1 |
Transmission | Germline | Strain of Origin | 129S4/SvJae |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The majority of the coding region (exons 4-9) was replaced with a neomycin resistance gene via homologous recombination. Western blot analysis of kidney and liver extracts from homozygous mutant animals did not detect gene expression. Enzyme activity was absent in liver extracts from homozygous mutant animals. |