| Primary Identifier | MGI:6509009 | Allele Type | Targeted |
| Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Ace2 |
| Transmission | Germline | Strain of Origin | C57BL/6NTac |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The targeting vector is designed to replace 71 kb (70,987bp) on the mouse X chromosome stretching from, but not including, collectrin, amino acid transport regulator (Cltrn) gene to BMX non-receptor tyrosine kinase (Bmx) gene with a syntenic 66 kb (65,812bp) region from the human X chromosome. A loxN-flanked neomycin resistance (neo) cassette was inserted at the junction between the human ACE2 and mouse Bmx genes. Transient cre-mediated recombination removed the floxed neo cassette. |
