First Author | Salomoni P | Year | 2002 |
Journal | Cell | Volume | 108 |
Issue | 2 | Pages | 165-70 |
PubMed ID | 11832207 | Mgi Jnum | J:76927 |
Mgi Id | MGI:2180610 | Doi | 10.1016/s0092-8674(02)00626-8 |
Citation | Salomoni P, et al. (2002) The role of PML in tumor suppression. Cell 108(2):165-70 |
abstractText | The PML gene, involved in the t(15;17) chromosomal translocation of acute promyelocytic leukemia (APL), encodes a protein which localizes to the PML-nuclear body, a subnuclear macromolecular structure. PML controls apoptosis, cell proliferation, and senescence. Here, we review the current understanding of its role in tumor suppression. |