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Comment :

Type  MGI:General Description  mice develop islet adenomas and carcinomas by 6-8 months of age islet tumor incidence is greater in females than males, though the difference is not statistically significant incidence of islet adenomas is greater than that of carcinomas tumors primarily consist of alpha-cells associated to varying degrees with other islet endocrine cell types vascular invasion by tumor cells is seen and lymphatic vessels containing tumor cells are seen occasionally