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Allele : F3<tm2Fct> coagulation factor III; targeted mutation 2, Felix C Tanner

Primary Identifier  MGI:7462664 Allele Type  Targeted
Gene  F3 Transmission  Germline
Strain of Origin  129P2/OlaHsd Is Recombinase  false
Is Wild Type  false
molecularNote  The coding region was replaced with a cDNA of the mouse gene containing a C213G mutation in exon 5 and a floxed neo cassette in inverse orientation via homologous recombination. This mutation disrupts the extracellular allosteric disulfide bond (Cys190-Cys213).
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • C213G Tf,
  • C213G Tf
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories