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Publication : The hairpin stack fold, a novel protein architecture for a new family of protein growth factors.

First Author  Hrabal R Year  1996
Journal  Nat Struct Biol Volume  3
Issue  9 Pages  747-52
PubMed ID  8784346 Mgi Jnum  J:35161
Mgi Id  MGI:82612 Doi  10.1038/nsb0996-747
Citation  Hrabal R, et al. (1996) The hairpin stack fold, a novel protein architecture for a new family of protein growth factors [letter]. Nat Struct Biol 3(9):747-52
abstractText  The granulin/epithelin protein motif has an unusual structure consisting of a parallel stack of beta-hairpins stapled together by six disulphide bonds. The new structure also contains a folding subdomain shared by small toxins, protease inhibitors as well as the EGF-like protein modules.
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