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Protein Coding Gene : Ccdc88b coiled-coil domain containing 88B

Primary Identifier  MGI:1925567 Organism  mouse, laboratory
Chromosome  19 NCBI Gene Number  78317
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable dynein light intermediate chain binding activity and microtubule binding activity. Involved in defense response to protozoan; positive regulation of T cell proliferation; and positive regulation of cytokine production. Located in membrane. Orthologous to human CCDC88B (coiled-coil domain containing 88B).
PHENOTYPE: Mice homozygous for a null ENU-induced allele exhibit decreased susceptibility to P. berghei infection with reduced T cell proliferation, decreased cytokine secretion and increased myeloid cell number. [provided by MGI curators]
  • synonyms:
  • Ccdc88b,
  • 2610041P08Rik,
  • coiled-coil domain containing 88B,
  • RIKEN cDNA 2610041P08 gene

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