| Primary Identifier | MGI:5754586 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Bcas1 |
| Strain of Origin | C57BL/6NCrl | Is Recombinase | false |
| Is Wild Type | false | Project Collection | IMPC |
| molecularNote | This allele produced from project TCPR0256 at The Centre for Phenogenomics by injecting Cas9 mRNA and one guide RNA with the spacer sequence GGTGCCAATGGGCCGGTGGC. This resulted in an insertion of 1 bp (A on the -1 strand) at Chr2:170406531 (GRCm38) in exon 4 (ENSMUSE00001221352). This mutation is predicted to cause a frameshift with amino acid changes after residue 169 and early truncation 6 amino acids later (p.T170Nfs*8). |
