| Primary Identifier | MGI:2386333 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(Lck-Nr4a1)2Brv |
| Strain of Origin | Not Specified | Is Recombinase | false |
| Is Wild Type | false |
| description | Founder 2 is representative of transgenic founders 2 and 4 exhibiting the highest levels of transgene expression that were used for analysis. |
| molecularNote | The mouse Nr4a1 cDNA fused to a mouse Lck proximal promoter was used as the transgene. Northern and Western blot analyses of thymus and thymocytes showed that RNA and protein expression is significantly increased in transgenic animals. Nuclear extracts from transgenic thymocytes also showed stronger DNA-binding activity compared to wild-type. |
