First Author | Christofori G | Year | 1999 |
Journal | Trends Biochem Sci | Volume | 24 |
Issue | 2 | Pages | 73-6 |
PubMed ID | 10098402 | Mgi Jnum | J:53102 |
Mgi Id | MGI:1331287 | Doi | 10.1016/s0968-0004(98)01343-7 |
Citation | Christofori G, et al. (1999) The role of the cell-adhesion molecule E-cadherin as a tumour-suppressor gene. Trends Biochem Sci 24(2):73-6 |
abstractText | E-cadherin-mediated cell-cell adhesion is lost during the development of most epithelial cancers. Recent evidence indicates that the loss of E-cadherin function, besides causing loss of cell-cell adhesion, might also convey signals that actively induce tumour-cell invasion and metastasis. |