Primary Identifier | MGI:5504510 | Allele Type | Targeted |
Attribute String | Reporter | Gene | Shox2 |
Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A targeting vector introduced the beta galactosidase coding sequence and an frt-flanked PGK-neo selection cassette into the Shox2 locus via homologous recombination in ES cells, replacing exon 1, intron 1 and part of exon 2. Germline animals were crossed to Flp deleter mice to remove the PGK-neo cassette. |