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Protein Domain : ZPR1 family

Primary Identifier  IPR040141 Type  Family
Short Name  ZPR1
description  This family consist of zinc finger protein ZPR1 and ZPR1-like proteins. The function of ZPR1 is not clear. ZPR1 is present in both the cytoplasm and nucleoplasma and its subcellular distribution changes during proliferation []. ZPR1 binds to the cytoplasmic tyrosine kinase domain of the epidermal growth factor receptor (EGFR) []and is a component of downstream signaling of both EGFR and FGFR signaling []. It has been associated with susceptibility to type 2 diabetes []and is downregulated in patients with spinal muscular atrophy [].

1 Child Features

0 Parent Features

10 Protein Domain Regions